TestMedica Guardian BioSciences is a medical biotechnology company offering diagnostic testing products, clinical chemistry reagents, instruments and other high quality diagnostic products for healthcare professionals in hospitals, physician offices, and occupational health centres and to consumers in the OTC markets worldwide.
 
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Testmedica lateral flow tests are also called immunochromatographic strip (ICS) tests. They have been a popular platform for rapid tests since their introduction in the late 1980s.




Testmedica ICS tests are used for the specific qualitative or semi-quantitative detection of many analytes including antigens, antibodies, and even the products of nucleic acid amplification tests. One or several analytes can be tested for simultaneously on the same strip. Urine, saliva, serum, plasma, or whole blood can be used as specimens. Extracts of patient exudates or fluids have also been successfully used.



Test sensitivity can be quite good. For example, hepatitis B surface antigen (HBsAg) ICS tests have claimed a sensitivity of 1.0 ng HBsAg/ml or less. Test specificity can also be very high. The tests use colloidal gold, dye, or latex bead conjugates to generate signal. The assembled strips are dried and packaged, making them stable for months when properly protected from moisture and excessive heat.



To perform the test, a sample, either used alone or with an extraction reagent or running buffer, is placed on the sample pad on one end of the strip. The signal reagent is solubilized and binds to the antigen or antibody in the sample and moves through the membrane by capillary action. If specific analyte is present, the signal reagent binds to it, and a second antibody or antigen -immobilized as a line in the nitrocellulose -then captures the complex. If the test is positive, a pink/purple line develops.



Once the specimen is added, the tests can be left unattended until they are read. The tests can be run individually or in limited-size batches.
 

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